Generic alternatives may be available. Acetaminophen and Codeine pronounced as a set a mee' noe fen koe' deen. Why is this medication prescribed?
How should this medicine be used? Other uses for this medicine What special precautions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names Brand names of combination products Other names.
Other uses for this medicine. What special precautions should I follow? Before taking acetaminophen and codeine, tell your doctor and pharmacist if you are allergic to acetaminophen, codeine, sulfite, any other medications, or any of the ingredients in acetaminophen and codeine products.
Ask your doctor or pharmacist for a list of the ingredients. Your doctor will probably tell you not to take acetaminophen and codeine if you are taking one or more of these medications, or have taken them within the past two weeks. Many other medications may also interact with acetaminophen and codeine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Your doctor may tell you not to take acetaminophen and codeine if you have any of these conditions. Talk to your doctor about the risks of taking acetaminophen and codeine.
You should not breastfeed while taking acetaminophen and codeine. Codeine can cause shallow breathing, difficulty or noisy breathing, confusion, more than usual sleepiness, trouble breastfeeding, or limpness in breastfed infants in breastfed infants.
Do not drive a car or operate machinery until you know how this medication affects you. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Acetaminophen and codeine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: constipation difficulty urinating Some side effects can be serious.
If you experience any of these symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical help: nausea, vomiting, loss of appetite, weakness, or dizziness agitation, hallucinations seeing things or hearing voices that do not exist , fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea red, peeling or blistering skin rash hives itching swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness difficulty breathing or swallowing inability to get or keep an erection irregular menstruation decreased sexual desire Acetaminophen and codeine may cause other side effects.
If someone takes more than the recommended dose of acetaminophen and codeine, get medical help immediately, even if the person does not have any symptoms. Symptoms of overdose may include the following: nausea vomiting loss of appetite sweating unusual bleeding or bruising pain in upper right part of the stomach yellowing of skin or eyes slow or shallow breathing difficulty breathing sleepiness unable to respond or wake up loss of muscle tone narrowed or widened pupils cold and clammy skin fainting slow heartbeat.
What other information should I know? Also, you shouldn't take other medications that contain acetaminophen or that might have sedative properties, including:. Tell your doctor about all prescription, non-prescription, and over-the-counter medications you're taking so they can check for interactions and adjust dosages as needed.
Having too much codeine in the body poses several risks. For one, the drug can be habit-forming, meaning it could cause a person to develop a dependence. If you've been taking Tylenol 3 for several weeks or longer and want to stop, talk to your doctor. They can help you taper off the drug safely by decreasing your dose slowly.
Suddenly stopping the medication may lead to withdrawal symptoms, including:. Even when taken as prescribed, codeine in Tylenol 3 has a high risk of dependence. If you think you are becoming dependent on the drug, talk to your doctor about treatment options, which may include medications to relieve withdrawal symptoms.
Your doctor can also refer you to a mental health professional or addiction treatment facility for longer-term treatment and support. For more mental health resources, see our National Helpline Database. Learn the best ways to manage stress and negativity in your life. Blough ER, Wu M.
Acetaminophen: Beyond pain and fever-relieving. Front Pharmacol. Identifying and treating codeine dependence: A systematic review. Med J Aust. The value of plasma acetaminophen half-life in antidote-treated acetaminophen overdosage.
Clin Pharmacol Ther. Ther Drug Monit. Toxicologic testing for opiates: Understanding false-positive and false-negative test results. Hemodynamic effects of methadone and dihydrocodeine in overdose. Clin Toxicol Phila. Medical Genetics Summaries. A case of codeine induced anaphylaxis via oral route. Allergy Asthma Immunol Res.
Acetaminophen and codeine. Updated May 5, Your Privacy Rights. Seizures: This medication may cause seizures. Seizures are more likely to occur when higher doses of this medication are taken. If you have a history of epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Serotonin syndrome: Although rare, severe reactions are possible when codeine is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors medications used to treat depression. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, or changes in mental state including delirium and agitation. Coma and death are possible. If you are taking antidepressants, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Infants born to mothers who have been taking codeine for long periods of time may experience dangerous withdrawal symptoms at birth. Breast-feeding: Acetaminophen, codeine, and caffeine pass into breast milk.
Some of the codeine dose is converted into morphine by the body, once it has been taken. For some people, this change happens much faster than for others. If this happens to a nursing mother, the baby is at risk of receiving a morphine overdose through the breast milk.
If you are breast-feeding and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. Children: The safety and effectiveness of using this medication have not been established for children under 12 years old.
Medications containing codeine should not be given to people under 18 years old for pain management after surgery to remove the tonsils and or adenoids. Non-prescription products containing codeine should not be used by people under 18 years old.
Recent evidence shows that young people who use opioids, including codeine, may be more likely to have problems with the misuse of medications and other substances later in life. Seniors: Seniors who take this medication may be more likely to experience side effects or worsening of preexisting medical conditions.
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:. An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed. Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter non-prescription , and herbal medications you are taking.
Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Codeine belongs to the group of medicines called narcotic analgesics pain medicines.
It acts on the central nervous system CNS to relieve pain. When codeine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence addiction is not likely to occur when narcotics are used for this purpose.
Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:.
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.
For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of acetaminophen and codeine combination oral suspension in children younger than 3 years of age. Safety and efficacy have not been established.
Use of acetaminophen and codeine combination oral solution or tablets is not recommended in children younger than 12 years of age. Acetaminophen and codeine combination should not be used to relieve pain after surgery to remove tonsils or adenoids in any children. Severe breathing problems and deaths have been reported in some children who received codeine after tonsil or adenoid surgery. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of acetaminophen and codeine combination in the elderly.
However, elderly patients are more likely to have age-related liver, kidney, heart, or lung problems, which may require caution and an adjustment in the dose for patients receiving acetaminophen and codeine combination. Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.
When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. The presence of other medical problems may affect the use of this medicine.
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